Resource Type

Journal Article 6

Year

2023 2

2017 1

2010 2

Keywords

cervical cancer 2

Biochemical indicators 1

Chinese women 1

Fingerprint spectral signatures 1

Hyperspectral imaging 1

Leaf lesion progression 1

Presymptomatic diagnosis 1

Spot blotch 1

calcifield lesion 1

cancer screening 1

cervical high-grade squamous intraepithelial lesion 1

cervical intraepithelial neoplasia 1

cervical lesion 1

conization 1

drug-coated balloon 1

high bleeding risk 1

high risk-human papilloma virus 1

human papillomavirus (HPV) genotyping 1

hysterectomy 1

left main 1

open ︾

Search scope:

排序： Display mode:

Improving the prognosis of pancreatic cancer: insights from epidemiology, genomic alterations, and therapeutic challenges

Frontiers of Medicine doi: 10.1007/s11684-023-1050-6

Abstract: Pancreatic cancer, notorious for its late diagnosis and aggressive progression, poses a substantial challenge owing to scarce treatment alternatives. This review endeavors to furnish a holistic insight into pancreatic cancer, encompassing its epidemiology, genomic characterization, risk factors, diagnosis, therapeutic strategies, and treatment resistance mechanisms. We delve into identifying risk factors, including genetic predisposition and environmental exposures, and explore recent research advancements in precursor lesions and molecular subtypes of pancreatic cancer. Additionally, we highlight the development and application of multi-omics approaches in pancreatic cancer research and discuss the latest combinations of pancreatic cancer biomarkers and their efficacy. We also dissect the primary mechanisms underlying treatment resistance in this malignancy, illustrating the latest therapeutic options and advancements in the field. Conclusively, we accentuate the urgent demand for more extensive research to enhance the prognosis for pancreatic cancer patients.

Keywords： pancreatic cancer     cancer screening     single cell     molecular alterations     precancerous lesion     therapy    

HTML PDF Collect

percutaneous coronary intervention of left main coronary artery disease: the importance of proper lesion

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 75-84 doi: 10.1007/s11684-022-0950-1

Abstract: who underwent percutaneous coronary intervention (PCI) for a de novo left main coronary artery lesioncardiovascular events (MACEs) including cardiac death, non-fatal myocardial infarction, and target lesionThe cohort was divided into two groups depending on weather the lesion preparation was done accordingIf the lesion preparation was done according to the guidelines, the MACE and TLR rates were 21.2lesion

Keywords： drug-coated balloon     left main     high bleeding risk     predilatation     calcifield lesion     percutaneous coronary    

HTML PDF Collect

Triage for management of cervical high-grade squamous intraepithelial lesion patients with positive margin

Yuya Dou, Xiaodan Zhang, Yang Li, Fenfen Wang, Xing Xie, Xinyu Wang

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 223-228 doi: 10.1007/s11684-017-0517-8

Abstract: this study is to guide a triage for the management of cervical high-grade squamous intraepithelial lesionThe rate of residual lesion was calculated, and the factors associated with residual lesion were analyzed

Keywords： cervical high-grade squamous intraepithelial lesion     conization     positive surgical margin     hysterectomy    

HTML PDF Collect

HPV prevalence and genotyping in the cervix of Chinese women

Shao-Ming WANG, Jing LI, You-Lin QIAO

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 259-263 doi: 10.1007/s11684-010-0095-5

Abstract: years, and aims to draw a definitive conclusion on HPV prevalence and genotyping in cervical cancer and precancerous

Keywords： human papillomavirus (HPV) genotyping     cervical cancer     precancerous lesions     Chinese women    

HTML PDF Collect

Clinical significance of human papilloma virus infection in the cervical lesions

Shuang LI, Yu-Han MENG, Hu TING, Jian SHEN, Ding MA

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 264-270 doi: 10.1007/s11684-010-0094-6

Abstract: Cervical lesions have been regarded as the common and frequently occurring diseases in China. Recently, the morbidity and youth tendency of cervical cancer have gradually increased. Cervical cancer, related with human papilloma virus (HPV) infection, has been one of the severest diseases threatening health and life of women, and is an infectious disease. The universality of HPV infection in the reproductive tract should not be ignored. The well-known risk factors of HPV infection in cervical lesions consist of high-risk sexual behaviors, immunosuppression, age, contraceptive methods, the concurrent infection of other sexually transmitted diseases, etc. The variation of cervical lesions induced by HPV infection is involved in the continuous pathological process, including the subclinical, latent, and persistent infection of high risk (HR)-HPV, chronic cervicitis with abnormal results of cytological examination, cervical intraepithelial neoplasia (CIN), and cervical cancer. The outcome of patients with HPV infection is influenced by many factors, such as HPV subtype dominance, persistent HPV infection, HPV loading dose, and multiple HPV infection. Controlling HR-HPV persistent infection should be an important strategy for reducing cervical lesions.

Keywords： cervical lesion     high risk-human papilloma virus     persistent infection     loading dose     cervical intraepithelial    

HTML PDF Collect

Fingerprint Spectral Signatures Revealing the Spatiotemporal Dynamics of Bipolaris Spot Blotch Progression for Presymptomatic Diagnosis Article

Fengle Zhu, Zhenzhu Su, Alireza Sanaeifar, Anand Babu Perumal, Mostafa Gouda, Ruiqing Zhou, Xiaoli Li, Yong He

Engineering 2023, Volume 22, Issue 3,   Pages 171-184 doi: 10.1016/j.eng.2022.10.006

Abstract: interpretable and could capture the unique characteristics of chlorotic and necrotic tissues along with lesion

Keywords： Hyperspectral imaging     Fingerprint spectral signatures     Spot blotch     Leaf lesion progression     Presymptomatic    

HTML PDF Collect

Title Author Date Type Operation

Improving the prognosis of pancreatic cancer: insights from epidemiology, genomic alterations, and therapeutic challenges

Journal Article

percutaneous coronary intervention of left main coronary artery disease: the importance of proper lesion

Journal Article

Triage for management of cervical high-grade squamous intraepithelial lesion patients with positive margin

Yuya Dou, Xiaodan Zhang, Yang Li, Fenfen Wang, Xing Xie, Xinyu Wang

Journal Article

HPV prevalence and genotyping in the cervix of Chinese women

Shao-Ming WANG, Jing LI, You-Lin QIAO

Journal Article

Clinical significance of human papilloma virus infection in the cervical lesions

Shuang LI, Yu-Han MENG, Hu TING, Jian SHEN, Ding MA

Journal Article

Fingerprint Spectral Signatures Revealing the Spatiotemporal Dynamics of Bipolaris Spot Blotch Progression for Presymptomatic Diagnosis

Fengle Zhu, Zhenzhu Su, Alireza Sanaeifar, Anand Babu Perumal, Mostafa Gouda, Ruiqing Zhou, Xiaoli Li, Yong He

Journal Article